Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital ...
Jan 18, 2018
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A compound developed by Johns Hopkins researchers that blocks glutamine metabolism can slow tumor growth, alter the tumor microenvironment and promote the production of durable and highly active anti-tumor T cells.
Nov 8, 2019
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Scientists have just made an important discovery as to how cancer-targeting 'Natural Killer' (NK) cells are fuelled in the body, which has significant implications for related therapies. They found that glutamine—vital ...
Jun 14, 2018
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Prostate cancer is the most commonly diagnosed malignancy and second leading cause of cancer-related deaths among men in the U.S. The challenge with prostate cancer is that the standard treatment methods in the advanced stage ...
Sep 30, 2015
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The importance of glutamine was made clear as a colon cancer specific metabolism. It is known that glutamine metabolism is important for pancreatic cancer, but the importance of glutamine metabolism for colon cancer has been ...
Jan 10, 2017
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The first mouse model of an aggressive form of kidney cancer has identified an Achilles' heel in the disease that could lead to new treatment approaches in humans, according to a study by researchers at the School of Medicine.
May 12, 2015
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A new combination of treatments safely decreased growth of pancreatic cancer in mice by preventing cancer cells from scavenging for fuel, a new study finds.
Oct 9, 2023
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Mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism, according to a study by The Wistar Institute published online ...
Jan 11, 2021
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66
Blocking the formation of filaments—multi-enzyme structures that fuel cancer activity—may offer new ways to control cancer cell proliferation, according to a new study led by Cornell researchers.
Mar 5, 2024
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22
In 2023, life expectancy in Korea will be 83.6 years, the third highest among OECD countries, and it is steadily increasing every year. As the proportion of the elderly population increases, the social cost of treating various ...
Oct 11, 2023
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