Immunology

Viral protein may help chickenpox virus spread within the body

The virus that causes chickenpox—varicella zoster virus (VZV)—possesses a protein that could enhance its ability to hijack white blood cells and spread throughout the body, according to new research published in PLOS ...

Immunology

Sleeping sickness by stealth

(Medical Xpress)—Stealth is a well-known concept in military tactics. Almost since the invention of radar, the hunt began for counter-technologies to hide aircraft and missiles from detection – most successfully by modifying ...

Diseases, Conditions, Syndromes

Viral decoys—how the Ebola virus leads the immune system astray

A research team from Tübingen and Göttingen has described in the renowned journal Cell Reports a new mechanism how the Ebola virus escapes the immune system. The virus causes infected cells to release decoys that inactivate ...

Medical research

New drug target for Ebola, Marburg viruses

Ebola and Marburg are among the most deadly viruses, with mortality rates from these infections ranging from 25% to 90%. While no drugs currently are available on the market to prevent infection from these viruses—they ...

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Glycoprotein

Glycoproteins are proteins that contain oligosaccharide chains (glycans) covalently attached to polypeptide side-chains. The carbohydrate is attached to the protein in a cotranslational or posttranslational modification. This process is known as glycosylation. In proteins that have segments extending extracellularly, the extracellular segments are often glycosylated. Glycoproteins are often important integral membrane proteins, where they play a role in cell–cell interactions. Glycoproteins also occur in the cytosol, but their functions and the pathways producing these modifications in this compartment are less well-understood.

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