Scientists have developed new drug compounds that thwart the pro-cancer activity of FOXM1, a transcription factor that regulates the activity of dozens of genes. The new compounds suppress tumor growth in human cells and ...
Jan 7, 2020
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359
More than 200 genes with novel and known roles in glioblastoma—the most aggressive type of brain cancer—offer promising new drug targets. Researchers from the Wellcome Sanger Institute, Addenbrooke's Hospital and their ...
Jul 29, 2020
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176
In patients with HER2-positive breast cancer, Tykerb (lapatinib) has been used both in combination with herceptin (trastuzumab) and as an alternative single-agent therapy for pre-surgery (neo-adjuvant) chemotherapy treatment. ...
Jan 16, 2012
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0
Artificial intelligence/machine learning involves the development of computer systems that perform tasks that would normally require human intelligence. AI/ML is used by people every day, for example, while using smart home ...
Dec 8, 2021
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44
USC researchers have discovered a secret sauce in the brain's vascular system that preserves the neurons needed to keep dementia and other diseases at bay.
Jun 24, 2019
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UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models. The findings, ...
Aug 10, 2022
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1109
Johnson and Johnson recently announced that it was halting a clinical trial for a new Alzheimer's drug after safety issues emerged. This latest failure adds to the dozens of large, costly clinical trials that have shown no ...
Jun 6, 2018
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14
Walking barefoot on sand "felt like walking on glass" for Keith Wenckowski, who has lived with type-one diabetes for more than two decades.
Mar 5, 2015
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16
A perplexing problem for people with recurring urinary tract infections (UTIs) is persistent pain, even after antibiotics have successfully cleared the bacteria.
Mar 1, 2024
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149
Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing. Now, ...
Apr 12, 2022
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