Scientists have discovered a new cellular pathway that can promote and support the growth of cancer cells. In a mouse model of melanoma, blocking this pathway resulted in reduction of tumor growth. The study, which appears ...
Jun 15, 2017
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Despite intense research, there's been much confusion regarding the exact role of a protein in a critical cancer-linked pathway. On one hand, the protein is described as a cell proliferation inhibitor, on the other, a cell ...
May 4, 2017
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A new Yale-led study detailing how blood vessels develop could lead to novel treatments of cardiovascular diseases as well as cancer.
May 4, 2017
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There is an old axiom among cell biologists meant to caution against making assumptions about how certain proteins function, and it involves a hypothetical Martian. If that Martian came to Earth and looked down at a school ...
Mar 13, 2017
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While investigating a potential therapeutic target for the ERK1 and 2 pathway, a widely expressed signaling molecule known to drive cancer growth in one third of patients with colorectal cancer, University of California San ...
May 17, 2016
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Colon cancer is one of the leading causes of cancer-related deaths worldwide, and researchers are hard at work to understand the disease's complex molecular underpinnings. In a new study out this month in the journal Cell ...
Dec 4, 2015
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Researchers at University of California, San Diego School of Medicine have discovered a self-regulating loop in the Hippo pathway, a signaling channel garnering increased attention from cancer researchers due to its role ...
Jun 26, 2015
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Zinc deficiency - long associated with numerous diseases, e.g. autism, lung cancer, prostate cancer, and ovarian cancers - can lead to activation of the Hedgehog signaling pathway, a biomolecular pathway that plays essential ...
Apr 16, 2015
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In a breakthrough in the understanding of how cancer does its deadly work, researchers at the University of Virginia School of Medicine have shown that many cancers - including nearly all pancreatic cancers - enslave and ...
Apr 6, 2015
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Scientists based at the University of Helsinki, Finland, have discovered a 'hidden' mechanism which could explain why some cancer therapies which aim to block tumour blood vessel growth are failing cancer trials.
Jan 30, 2015
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