Psychology & Psychiatry

Psychedelic drugs: how the brains of informed users are different

There is a new generation of drug users out there who possess highly detailed pharmacological and technical knowledge about the drugs they take. "Psychonauts" (meaning "navigator of the soul") are enthusiastic and deliberate ...

Medications

A first look at how the drug salvinorin A works in the brain

Recent interest in developing therapies from hallucinogenic drugs has scientists exploring how these chemicals work in the brain. Recently, Johns Hopkins Medicine researchers imaged the brains of people who had vaped salvinorin ...

Psychology & Psychiatry

Discovering hallucinogenic mushrooms in Mexico

Before being qualified as "magic" and becoming the global phenomenon they are today, certain mushrooms were considered as sacred by the Mesoamerican peoples of Mexico. In the Nahuatl language the word teonanacatl, literally ...

Neuroscience

Mouse study examines the underpinnings of hallucinations

Hallucinations result in dramatic disruptions in perception and cognition, but the changes in brain activity that underlie such alterations are not well understood. In a study publishing March 26 in the journal Cell Reports, ...

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Hallucinogen

This general group of pharmacological agents can be divided into three broad categories: psychedelics, dissociatives, and deliriants. These classes of psychoactive drugs have in common that they can cause subjective changes in perception, thought, emotion and consciousness. Unlike other psychoactive drugs, such as stimulants and opioids, these drugs do not merely amplify familiar states of mind, but rather induce experiences that are qualitatively different from those of ordinary consciousness. These experiences are often compared to non-ordinary forms of consciousness such as trance, meditation, and dreams.

Hollister's criteria for establishing that a drug is hallucinogenic is:

Not all drugs produce the same effect and even the same drug can produce different effects in the same individual on different occasions.

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