Medications

How drugs can target the thick 'scar tissue' of pancreatic cancer

Pancreatic cancer is one of the deadliest cancers—only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar ...

Oncology & Cancer

Epigenetically acting drugs could support cancer immunotherapy

Epigenetically active drugs enable the cell to read parts oft he genome that were previously blocked and inaccessible. This leads to the formation of new mRNA transcripts and also new proteins, as scientists from the German ...

Oncology & Cancer

Researchers identify a novel player in acute myeloid leukemia

A new study led by scientists at Sanford Burnham Prebys has shown that the protein RNF5 plays an unusual role in acute myeloid leukemia (AML). Unlike its expected role, marking aberrant proteins for destruction, RNF5 binds ...

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