Genetics

Mutation puts women at higher risk of heart failure

When the PRDM16 gene mutates, heart muscle cells undergo changes in their metabolism. This increases the risk of congenital heart failure in women more than men, as a ECRC research team led by Sabine Klaassen and Jirko Kühnisch ...

Cardiology

What happens to our cardiovascular system as we age?

With every pump of our heart, blood courses through our arteries and veins, carrying oxygen and nutrients through our body. But as we age, blood vessels can stiffen, blockages can build up, and the system may become prone ...

Oncology & Cancer

How silencing a gene-silencer could lead to new cancer drugs

Deep inside our cells— each one complete with an identical set of genes— a molecular machine known as PRC2 plays a critical role in determining which cells become heart cells, vs. brain or muscle or skin cells.

Immunology

Reducing stress on T cells makes them better cancer fighters

Even for killer T cells—specialized immune cells—seeking and destroying cancer cells around the clock can be exhausting. If scientists can understand why killer T cells become exhausted, then they can create more resilient ...

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