In people, a baby's risk of congenital heart defects is associated with the age of the mother. Risk goes up with increasing age. Newborn mice predisposed to heart defects because of genetic mutations show the same age association.
Apr 1, 2015
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Fetal ultrasound exams on more than 87,000 mice that were exposed to chemicals that can induce random gene mutations enabled developmental biologists at the University of Pittsburgh School of Medicine to identify mutations ...
Mar 25, 2015
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(Medical Xpress)—A rare genetic disorder known as Jacobsen syndrome has been linked with autism, according to a recent joint investigation by researchers at San Diego State University and the University of California, San ...
Sep 15, 2014
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Scientists at the University of East Anglia have made an important step in understanding how hearts are formed in developing embryos.
May 5, 2014
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A type of cell that builds mouse hearts can renew itself, Johns Hopkins researchers report. They say the discovery, which likely applies to such cells in humans as well, may pave the way to using them to repair hearts damaged ...
Apr 30, 2014
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When a child is born with a heart defect such as a hole in the heart, the highly invasive therapies are challenging due to an inability to quickly and safely secure devices inside the heart. Sutures take too much time to ...
Jan 8, 2014
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(Medical Xpress)—The search for the cause of devastating birth defects has led Yale School of Medicine researchers to a key insight into the biology of embryonic development.
Nov 14, 2013
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Mitochondria are the power plants of cells, manufacturing chemical fuel so a cell can perform its many tasks. These cellular power plants also are well known for their role in ridding the body of old or damaged cells.
Oct 3, 2013
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Folic acid deficiency can cause severe health problems in offspring, including spina bifida, heart defects and placental abnormalities. A study out today reveals that a mutation in a gene necessary for the metabolism of folic ...
Sep 26, 2013
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(Medical Xpress)—In a first-of-its-kind study published in the journal Nature, scientists identified a group of gene mutations that may be behind up to 10 percent of complex congenital heart defects, the most frequent birth ...
Jul 24, 2013
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