Medical research

A step toward understanding gastric cancer

Helicobacter pylori infects approximately half of the world's population and is the strongest known risk factor for developing gastric cancer. Gastric cancer is the third most lethal cancer worldwide.

Oncology & Cancer

Scientists discover origin of cell mask that hides stomach cancer

A layer of cells that look like normal stomach lining on top of sites of stomach cancer can make it difficult to spot after removal of a Helicobacter pylori infection. In a recent study, researchers from Hiroshima University ...

Medical research

Advanced computational modeling of the gut for biodefense

The Nutritional Immunology and Molecular Medicine Laboratory (NIMML) has developed a high-resolution model of the gut immune system by using advanced computational systems. The new high-performance computing (HPC)-driven ...

Oncology & Cancer

Pathogens find safe harbor deep in the gastric glands

Scientists have long tried to understand how pathogenic bacteria like Helicobacter pylori, a risk factor for stomach ulcers and cancer, survive in the harsh environment of the stomach. In a new study publishing May 2 in the ...

Medical research

New study explains how inflammation causes gastric cancer

In 1982, researchers reported a link between chronic gastritis and stomach bacterium Helicobacter pylori, triggering a flurry of research into this newly identified pathogen. These studies made it clear that in addition to ...

Oncology & Cancer

Probing H. pylori cancer protein

Infection with the stomach-dwelling bacterium Helicobacter pylori— particularly strains producing the oncoprotein CagA—is a strong risk factor for gastric cancer.

Immunology

Toxin floats on lipid rafts

Helicobacter pylori, the leading cause of peptic ulcer disease and stomach cancer. One factor important to H. pylori infection is the pore-forming toxin VacA. It is thought to gain entry into host cells by binding to specialized ...

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