Medical research

Key stem cell dormancy mechanism discovered

Princess Margaret Cancer Centre researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number ...

Medical research

Perfecting collagen production in osteogenesis imperfecta

Most people can expect to break close to two bones in their lifetime, but those with osteogenesis imperfecta—also known as brittle bone disease—can break hundreds of bones before they even hit puberty. And while healthy ...

Oncology & Cancer

Sensing 'junk' RNA after chemotherapy enhances blood regeneration

Chemotherapy is widely used to treat cancer patients. During the treatment, chemotherapeutic agents affect various biochemical processes to kill or reduce the growth of cancer cells, which divide uncontrollably in patients. ...

Oncology & Cancer

Two studies explore link between inflammation and leukemia

Two recent collaborative publications by CU Cancer Center members provide insights into how chronic inflammation can serve as a key factor in the development of leukemia and other blood cancers.

Oncology & Cancer

Blood stem cells make brain tumors more aggressive

For the first time, scientists from the German Cancer Consortium (DKTK) partner site in Essen/Düsseldorf have discovered stem cells of the hematopoietic system in glioblastomas, the most aggressive form of brain tumor. These ...

Medical research

Using base editing to treat sickle cell disease in mice

A team of researchers from the Broad Institute, Harvard University and St. Jude Children's Research Hospital has used a base editing technique in a novel way to treat sickle cell disease (SCD) in mice. In their paper published ...

Oncology & Cancer

An antibody-drug combo to combat cancer

Leukemias are debilitating cancers of the hematopoietic or blood-forming cells of the bone marrow. Now, researchers at Tokyo Medical and Dental University (TMDU) describe an ingenious strategy against chronic myelomonocytic ...

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