Two teams of researchers working independently have found success in trialing gene therapies targeting sickle-cell anemia. Both teams have published papers in the New England Journal of Medicine describing their work and ...
Scientists are seeing promising early results from the first studies testing gene editing for painful, inherited blood disorders that plague millions worldwide, especially Black people.
Dec 5, 2020
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When Lamarcus Jean visits the Hematology Clinic at Dana-Farber/Boston Children's Cancer and Blood Disorders Center, he makes himself right at home. The 6-year-old, whom his mom, Stephanie, describes as "wise beyond his years," ...
Jan 28, 2020
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In a paper published in the July 31 issue of Science Translational Medicine, researchers at Fred Hutchinson Cancer Research Center used CRISPR-Cas9 to edit long-lived blood stem cells to reverse the clinical symptoms observed ...
Jul 31, 2019
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Help for patients with sickle cell disease may soon come from gene editing to fix the mutation that causes the disease and boost the patient's own protective fetal hemoglobin.
Jun 3, 2019
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Biomedical engineers have developed a smartphone app for the non-invasive detection of anemia. Instead of a blood test, the app uses photos of someone's fingernails taken on a smartphone to accurately measure how much hemoglobin ...
Dec 4, 2018
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Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease (SCD). Experiments ...
Jul 19, 2018
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Our ability to breathe oxygen is critical to our survival. This process is mediated by the hemoglobin in our blood, which carries oxygen. Since air contains less oxygen on high mountains, the body is under pressure to make ...
Apr 4, 2017
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An international team of scientists led by researchers at St. Jude Children's Research Hospital has found a way to use CRISPR gene editing to help fix sickle cell disease and beta-thalassemia in blood cells isolated from ...
Aug 15, 2016
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An interdisciplinary, international group of researchers has found new biophysical markers that could help improve the understanding of treatments for sickle cell disease, a step toward developing better methods for treating ...
Aug 8, 2016
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