Oncology & Cancer

Histone deacetylase 6 inhibition enhances oncolytic viral therapy

Gliomas are extremely aggressive brain tumors that are resistant to standard cancer therapeutics. Oncolytic viral (OV) therapy, which uses engineered viruses to infect and target tumor cells for destruction by the immune ...

Obstetrics & gynaecology

Herpes simplex virus can mimic premature rupture of membranes

(HealthDay)—Unique presentation of herpes simplex virus infection in pregnancy can be misdiagnosed as premature rupture of membranes (PROM), according to a case report published in the August issue of Obstetrics & Gynecology.

Oncology & Cancer

ASCO: Risks of whole brain radiotx may outweigh benefits

(HealthDay)—Targeted radiation in the treatment of brain metastases leads to less cognitive damage than radiation for the entire brain, while survival is similar, researchers reported Sunday at the annual meeting of the ...

Medical research

Radical vaccine design effective against herpes viruses

Herpes simplex virus infections are an enormous global health problem and there is currently no viable vaccine. For nearly three decades, immunologists' efforts to develop a herpes vaccine have centered on exploiting a single ...

Immunology

Research team uncovers genetic trigger for immune response

The thousands of mitochondrial DNA (mtDNA) molecules present in each cell are known primarily for their role converting food and oxygen into energy. But Yale researchers have identified an unexpected relationship between ...

Diseases, Conditions, Syndromes

New worldwide estimates for herpes simplex virus type 2 published

New global estimates for herpes simplex virus type 2 show that over 400-million people worldwide were infected with the virus in 2012. The estimates underline the extent to which herpes simplex virus type 2 – the virus ...

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