Mutations in a subunit of a receptor that binds the major inhibitory neurotransmitter GABAA in the brain have been linked, through a common mechanism, to epilepsy, autism and intellectual disability, researchers at Vanderbilt ...
Oct 4, 2019
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259
Until now, there has been no adequate treatment available for the rare and highly aggressive malignant blood disease T-PLL leukaemia. By screening blood samples from patients with haematological diseases, a team of doctors ...
Oct 24, 2017
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19
For women with ovarian cancer, there is a high rate of mortality, in part due to the ease of cancer cell spreading, or metastasis, in the abdominal cavity. Current treatments can be expensive and have proven to be ineffective ...
Dec 28, 2021
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113
McMaster University researchers have discovered a combination punch to treat drug-resistant infections that is showing promise based on testing in mice.
May 14, 2020
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26
Research led by Peking University, China, has looked into gut microbiota production of isozymes, which do similar work to human enzymes but have different structures.
Pediatric encephalopathies of genetic origin cause severe motor and intellectual disabilities from birth. One of these diseases, first identified in 2013, is caused by mutations in the GNAO1 gene. In order to understand the ...
Oct 10, 2022
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60
Tuberculosis treatment still entails the administration of several antibiotics over a period of months and is torturous for many patients. The pathogen's increasing multidrug resistance additionally complicates this lengthy ...
Feb 12, 2019
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64
Many neurodegenerative conditions, from glaucoma to Alzheimer's disease, are characterized by injury to axons—the long, slender projections that conduct electrical impulses from one nerve cell to another, facilitating cellular ...
Dec 14, 2020
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354
A McMaster researcher is part of a team that has developed a more efficient way to screen for vitamin D deficiency that could become a tool in the fight against COVID-19 and other respiratory illnesses.
Apr 15, 2022
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50
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have for the first time discovered a killing mechanism that could underpin a range of the most intractable neurodegenerative diseases such as Alzheimer's, ...
Feb 12, 2015
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