Medical research
Epilepsy treatment could yield cure for McArdle disease
WA scientists may have found a cure for the crippling muscle condition McArdle disease, using a drug already approved for use in humans.
Jan 15, 2015
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News tagged with histone deacetylase inhibitors
Oncology & Cancer
New research identifies potential drug treatment for advanced eye cancer
An international team of researchers led by University College Dublin (UCD) have uncovered a potential treatment approach for advanced uveal melanoma (UM), a type of cancer that effects the eye.
May 20, 2022
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Medications
New drug combination shows promise in treating acute myeloid leukemia
Research led by Peter Mac and published in Cancer Discovery has found a new combination therapy for acute myeloid leukemia (AML) that shows greater potency in a preclinical study than either drug used alone.
Jun 1, 2022
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Medications
An anti-cancer drug acts as an epigenetic memory aid, scientists find
EPFL scientists have discovered how an anti-cancer drug could be repurposed to improve memory. It does so by supporting the cell's ability to read the very genes that are important for learning. The epigenetic mechanism of ...
Jun 13, 2022
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Diabetes
Drug abuse during pregnancy can cause diabetes in children later in life
Data from the U.S. indicate that between 5 to 10 percent of mothers consume psychostimulants (such as amphetamine, cocaine or methamphetamine) during pregnancy. Apart from the negative impacts on the developing brain, many ...
Nov 21, 2019
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Neuroscience
Basic research shows that drug used to treat multiple sclerosis may have beneficial effects on memory
(Medical Xpress)—Virginia Commonwealth UniversitySchool of Medicine researchers have uncovered a new mechanism of action of fingolimod, a drug widely used to treat multiple sclerosis: elimination of adverse or traumatic ...
May 28, 2014
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Oncology & Cancer
New discovery in understanding chemotherapy resistance could prevent cancer cells fighting back
Scientists have made an important breakthrough in understanding why some cancer cells become resistant to chemotherapy.
Oct 28, 2016
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Oncology & Cancer
Benefit of novel drug in breast cancer seen in blood within weeks
Clinical benefit from use of a novel histone deacetylase inhibitor drug may be determined by examining blood cells days after a patient receives treatment. The drug, entinostat, is the first histone deacetylase inhibitor ...
Nov 13, 2011
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Genetics
Changes in gene explain more of inherited risk for rare disease
(Medical Xpress)—Changes to a gene called LZTR1 predispose people to develop a rare disorder where multiple tumors called schwannomas form near nerve pathways, according to a study published today in the journal Nature ...
Dec 24, 2013
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Oncology & Cancer
Potential new treatments for acute myeloid leukemia
Two separate studies yield key findings for the prevention, diagnosis, treatment and cure for acute myeloid leukemia (AML). AML is a group of heterogeneous diseases with considerable diversity in terms of genetic abnormalities. ...
Nov 25, 2013
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