Oncology & Cancer

Approving children's cancer drugs takes 6.5 years longer

(HealthDay)—For cancer drugs ultimately approved by the U.S. Food and Drug Administration, the median lag time from first-in-human to first-in-child trials is 6.5 years, according to a study published in the May issue of ...

Medical research

Researchers spot mutations that crop up in normal cells as we age

Cell division is not perfect. As we get older, mutations often appear in genes in normal cells. Most of these mutated cells and their progeny—called "somatic clones"—have no effect on our health, but a tiny fraction can ...

Medical research

Studying the function of liver cancer genes in mini-organs

Researchers from the Hubrecht Institute and Radboud University have developed a human model in which they use organoids, or mini organs, to study the function of specific genes that are mutated in liver cancer. Using this ...

Oncology & Cancer

Conquering cancer's infamous KRAS mutation

KRAS is one of the most challenging targets in cancer. Despite its discovery more than 60 years, researchers still struggle to inhibit its mutated form—earning its reputation as "undruggable." Yet, the hunt for an Achilles' ...

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