Oncology & Cancer

Signature of an ineffective immune response to cancer revealed

Our immune system is programmed to destroy cancer cells. Sometimes it has trouble slowing disease progression because it doesn't act quickly or strongly enough. In a study published in The Journal of Clinical Investigation, ...

Oncology & Cancer

Approving children's cancer drugs takes 6.5 years longer

(HealthDay)—For cancer drugs ultimately approved by the U.S. Food and Drug Administration, the median lag time from first-in-human to first-in-child trials is 6.5 years, according to a study published in the May issue of ...

Medical research

Researchers spot mutations that crop up in normal cells as we age

Cell division is not perfect. As we get older, mutations often appear in genes in normal cells. Most of these mutated cells and their progeny—called "somatic clones"—have no effect on our health, but a tiny fraction can ...

Medical research

Studying the function of liver cancer genes in mini-organs

Researchers from the Hubrecht Institute and Radboud University have developed a human model in which they use organoids, or mini organs, to study the function of specific genes that are mutated in liver cancer. Using this ...

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