Medical research

Stem cell signal drives new bone building

In experiments in rats and human cells, Johns Hopkins Medicine researchers say they have added to evidence that a cellular protein signal that drives both bone and fat formation in selected stem cells can be manipulated to ...

Medical research

Stem-cell-growing surface enables bone repair

(Medical Xpress) -- University of Michigan researchers have proven that a special surface, free of biological contaminants, allows adult-derived stem cells to thrive and transform into multiple cell types. Their success brings ...

Genetics

The promise of stem cell-based gene therapy

Sophisticated genetic tools and techniques for achieving targeted gene delivery and high gene expression levels in bone marrow will drive the successful application of gene therapy to treat a broad range of diseases. Examples ...

Medical research

To treat rare disease, NIH scientists repurpose FDA-approved drug

A new study reports that a drug already approved by the Food and Drug Administration for use in patients undergoing a bone marrow transplant may also have promise for treating people who have a rare immune deficiency known ...

Genetics

Another byproduct of aging: Hypermutations in the brain

Genetic mutations in early development have been implicated in several psychiatric disorders such as autism and schizophrenia, symptoms of which typically manifest during childhood and early adulthood. However, mutations ...

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