Diseases, Conditions, Syndromes

Promoting mixed chimerism promising in kidney transplants

(HealthDay)—For patients undergoing living kidney transplants, persistent mixed chimerism can be achieved to allow complete or partial withdrawal of immunosuppressive drugs, according to a study published in the Jan. 29 ...

Oncology & Cancer

Allo-HCT with unrelated donor tied to better outcomes in AML

(HealthDay)—Allogeneic hematopoietic cell transplantation (allo-HCT) with an unrelated donor (UD) results in better transplantation outcomes than cord blood transplantation (CBT) in acute myeloid leukemia (AML) patients ...

Genetics

Big data provides clues for characterizing immunity in Japanese

Although genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6 in a segment called the major histocompatibility complex (MHC) region. The density ...

Genetics

Keeping aging brains healthy—lessons from genes

Do any genes protect against Alzheimer's disease? And do any predispose a person to its ravages? The answer is yes to both, according to work led by U of M researcher Lisa James.

Diseases, Conditions, Syndromes

A risk factor for drug-induced skin disease identified

DPP-4 inhibitor (DPP-4i) is widely used to treat type 2 diabetes, but increased cases of bullous pemphigoid (BP) have been reported among patients taking the medicine. BP is the most common autoimmune blistering disorder, ...

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