(HealthDay)—Allogeneic hematopoietic cell transplantation (allo-HCT) with an unrelated donor (UD) results in better transplantation outcomes than cord blood transplantation (CBT) in acute myeloid leukemia (AML) patients ...
Jun 4, 2019
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Although genes are distributed widely across chromosomes, many genes related to the immune system are clustered together on human chromosome 6 in a segment called the major histocompatibility complex (MHC) region. The density ...
Jan 29, 2019
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Do any genes protect against Alzheimer's disease? And do any predispose a person to its ravages? The answer is yes to both, according to work led by U of M researcher Lisa James.
Nov 27, 2018
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Using RNA interference (RNAi) technology to silence an immune-stimulating complex in endothelial cells (EC), the main cellular component of blood vessels, researchers have made it possible to use the plentiful supply of donor ...
Feb 7, 2018
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Cancer cells arise when DNA is mutated, and these cells should be recognized as "foreign" by the immune system. However, cancer cells have found ways to evade detection by the immune system.
Dec 15, 2017
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DPP-4 inhibitor (DPP-4i) is widely used to treat type 2 diabetes, but increased cases of bullous pemphigoid (BP) have been reported among patients taking the medicine. BP is the most common autoimmune blistering disorder, ...
Dec 6, 2017
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Human leukocyte antigen (HLA)-G is a protein that interacts with specific cell receptors to inhibit immune responses. The protein is best known for its role in protecting the fetus from attack by its mother's immune system. ...
Aug 4, 2017
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A study led by researchers at Vanderbilt University Medical Center (VUMC) and the University of Arizona College of Pharmacy has generated the first comprehensive catalog of diseases associated with variations in human leukocyte ...
May 10, 2017
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A number of genetic variants associated with susceptibility to oral cavity and pharyngeal cancer have been described in an international study published in the journal Nature Genetics. The most noteworthy finding was an association ...
Dec 16, 2016
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Veterans Affairs researchers have found that certain forms, or alleles, of a gene known to play a key role in the immune system appear to offer protection from Gulf War illness (GWI). Further, they discovered how such protection ...
Nov 17, 2016
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