A "humanized" mouse model equipped with the immune system of a patient who needs an organ transplant beats current measures for identifying the best potential living donor, scientists report.
Aug 27, 2021
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Researchers at the Cheriton School of Computer Science have applied machine learning to identify tumor-specific antigens, which could help make personalized cancer vaccines practically feasible and more accurate.
Apr 30, 2021
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A paper by a multidisciplinary team of scientists affiliated with various Brazilian institutions, including the University of São Paulo (USP) and the National Cancer Institute (INCA), shows that people of African descent ...
Feb 2, 2021
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New research into the HIV-1 virus has shed light on an important factor in the evolution of viruses, which is likely also to affect SARS-CoV-2 (the virus which causes COVID-19). This new insight could have important implications ...
Nov 19, 2020
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According to results from a Phase I/IIa trial at The University of Texas MD Anderson Cancer Center, treatment with cord blood-derived chimeric antigen receptor (CAR) natural killer (NK)-cell therapy targeting CD19 resulted ...
Feb 5, 2020
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(HealthDay)—For patients undergoing living kidney transplants, persistent mixed chimerism can be achieved to allow complete or partial withdrawal of immunosuppressive drugs, according to a study published in the Jan. 29 ...
Jan 30, 2020
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(HealthDay)—Allogeneic hematopoietic cell transplantation (allo-HCT) with an unrelated donor (UD) results in better transplantation outcomes than cord blood transplantation (CBT) in acute myeloid leukemia (AML) patients ...
Jun 4, 2019
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Do any genes protect against Alzheimer's disease? And do any predispose a person to its ravages? The answer is yes to both, according to work led by U of M researcher Lisa James.
Nov 27, 2018
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DPP-4 inhibitor (DPP-4i) is widely used to treat type 2 diabetes, but increased cases of bullous pemphigoid (BP) have been reported among patients taking the medicine. BP is the most common autoimmune blistering disorder, ...
Dec 6, 2017
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Human leukocyte antigen (HLA)-G is a protein that interacts with specific cell receptors to inhibit immune responses. The protein is best known for its role in protecting the fetus from attack by its mother's immune system. ...
Aug 4, 2017
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