Immunology

How the thymus trains T cells to fight infections

T cells are a special class of white blood cells that patrol the body and attack infected or foreign tissue. They learn to distinguish friendly proteins from dangerous ones in an organ called the thymus. However, when T cells ...

Medical research

Scientists build whole functioning thymus from human cells

Researchers at the Francis Crick Institute and University College London have rebuilt a human thymus, an essential organ in the immune system, using human stem cells and a bioengineered scaffold. Their work is an important ...

Immunology

Researchers generate developmental map of human T-cells

Chintan Parekh, MD, of the The Saban Research Institute of Children's Hospital Los Angeles, has led a team of investigators that generated a comprehensive roadmap for how T-cells develop in the human thymus. The study will ...

Immunology

Stem-cell-based strategy boosts immune system in mice

Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, the tissue can ...