Diseases, Conditions, Syndromes

New research sheds light on vision loss in Batten disease

Progressive vision loss, and eventually blindness, are the hallmarks of juvenile neuronal ceroid lipofuscinosis (JNCL) or CLN3-Batten disease. New research shows how the mutation associated with the disease could potentially ...

Medical research

A rift in the retina may help repair the optic nerve

In experiments in mouse tissues and human cells, Johns Hopkins Medicine researchers say they have found that removing a membrane that lines the back of the eye may improve the success rate for regrowing nerve cells damaged ...

Genetics

NHGRI publishes new vision for human genomics

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), this week published its "Strategic vision for improving human health at The Forefront of Genomics" in the journal Nature. ...

Genetics

Gene therapy targets inner retina to combat blindness

Gene therapy to the inner retina prevented blindness in a mouse model of the neuro-degenerative disorder CLN3 Batten disease. Adeno-associated viral (AAV)-mediated expression of the human CLN3 gene led to significant survival ...

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