Medications

FDA approves new antibiotic for three indications

The U.S. Food and Drug Administration has approved the antibiotic Zevtera (ceftobiprole medocaril sodium for injection) for three different indications, including treatment of adults with Staphylococcus aureus bloodstream ...

Gastroenterology

Anti-reflux mucosectomy effective for GERD in long term

For patients with gastroesophageal reflux disease (GERD), anti-reflux mucosectomy (ARMS) shows long-term efficacy and is also effective for patients with reflux hypersensitivity, according to a study published online June ...

Diseases, Conditions, Syndromes

Fatty acid affects sensitivity of psoriasis plaques to heat, pain

A common fatty acid found in the Western diet breaks down into compounds that contribute to increased temperature and pain—but not itch—sensitivity in psoriatic lesions. The finding could lead to better understanding ...

Medications

FDA approves first cell-based gene therapy for beta-thalassemia

The U.S. Food and Drug Administration has approved Zynteglo (betibeglogene autotemcel), the first cell-based gene therapy for the treatment of adult and pediatric patients with beta-thalassemia who require regular red blood ...

Radiology & Imaging

Allergic-like CT contrast reaction raises MRI contrast risk

People with a history of allergic-like reactions to iodinated contrast media, which is used in a variety of X-ray-based procedures, such as CT and angiography, are susceptible to similar reactions from commonly used MRI contrast ...

Medical research

Breyanzi approved for certain types of large B-cell lymphoma

Cell-based gene therapy Breyanzi (lisocabtagene maraleucel) has been approved to treat adults with certain types of large B-cell lymphoma who have not responded to other systemic treatment, the U.S. Food and Drug Administration ...

Medications

Antibody cocktail enhances clearance of SARS-CoV-2 virus

(HealthDay)—An interim analysis of data from an ongoing phase 1 to 3 trial shows that an antibody cocktail enhances clearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, according to a study published ...

Genetics

Insights into the genetic architecture of penicillin allergy

Researchers announce the first robust evidence for the role of the major histocompatibility complex gene HLA-B in penicillin allergy. To identify genetic risk factors for penicillin allergy, the international team of researchers ...

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Hypersensitivity

Hypersensitivity (also called hypersensitivity reaction) refers to undesirable reactions produced by the normal immune system. These reactions may be damaging, uncomfortable, or occasionally fatal. Hypersensitivity reactions require a pre-sensitized (immune) state of the host. The four-group classification was expounded by P. H. G. Gell and Robin Coombs in 1963.

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