Many people with autism experience sensory hypersensitivity, attention deficits, and sleep disruption. One brain region that has been implicated in these symptoms is the thalamic reticular nucleus (TRN), which is believed ...
Jul 22, 2020
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A common fatty acid found in the Western diet breaks down into compounds that contribute to increased temperature and pain—but not itch—sensitivity in psoriatic lesions. The finding could lead to better understanding ...
Jan 3, 2023
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According to the National Autism Association, people with autism spectrum disorder (ASD) may experience sensory hypersensitivity. A University of Minnesota Medical School researcher recently published an article in Nature ...
May 29, 2020
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An FDA-approved drug can reverse an ionic imbalance in neurons that leads to hyper-excitability in mice modeling an autism-related genetic disorder, according to a Northwestern Medicine study published in Molecular Psychiatry.
May 8, 2018
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Non-narcotic treatments for chronic pain that work well in people, not just mice, are sorely needed. Drawing from human pain genetics, an international team led by Boston Children's Hospital demonstrates a way to break the ...
Jun 17, 2015
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A study published in the scientific journal Nature Neuroscience by Yves De Koninck and Robert Bonin, two researchers at Université Laval, reveals that it is possible to relieve pain hypersensitivity using a new method that ...
Jul 9, 2014
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A research team led by a Howard Hughes Medical Institute investigator at the University of California, San Francisco has identified a genetic mutation that is strongly associated with a typical form of migraine.
May 1, 2013
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A brain pathway that is stimulated by traumatic or fearful experiences can be disrupted by two compounds that show promise for preventing post-traumatic stress disorder, Indiana University researchers reported.
Oct 15, 2012
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Adverse drug reactions are a major issue that cause harm, are costly and restrict treatment options for patients and the development of new drugs. A groundbreaking finding by researchers from the La Jolla Institute for Allergy ...
May 29, 2012
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The U.S. Food and Drug Administration has approved the antibiotic Zevtera (ceftobiprole medocaril sodium for injection) for three different indications, including treatment of adults with Staphylococcus aureus bloodstream ...
Apr 9, 2024
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Hypersensitivity (also called hypersensitivity reaction) refers to undesirable reactions produced by the normal immune system. These reactions may be damaging, uncomfortable, or occasionally fatal. Hypersensitivity reactions require a pre-sensitized (immune) state of the host. The four-group classification was expounded by P. H. G. Gell and Robin Coombs in 1963.
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