Diseases, Conditions, Syndromes

A novel defense mechanism for SARS-CoV-2 discovered

Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune ...

Oncology & Cancer

Inactive receptor renders cancer immunotherapies ineffective

The aim of immunotherapies is to enable the immune system to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose. However, they are only effective in about one-third ...

Other

App lets amputees program their own bionic hands

Double-amputee Jason Koger used to fly to visit a clinician when he wanted to adjust the grips on his bionic hands. Now, he's got an app instead. Koger this week demonstrated the i-limb ultra revolution, a prosthetic developed ...

Immunology

Autoimmune disease—retraining white blood cells

Symptoms of an autoimmune disease disappeared after a team of scientists retrained the white blood cells. This method is extremely promising for treating diseases such as type I diabetes and multiple sclerosis.

Genetics

Genetic clues to causes of primary biliary cirrhosis

Researchers have newly identified three genetic regions associated with primary biliary cirrhosis (PBC), the most common autoimmune liver disease, increasing the number of known regions associated with the disorder to 25.

Diabetes

Antibodies reverse type 1 diabetes in new immunotherapy study

Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections ...

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