Immunology

Life-threatening lung disease averted in experimental models

Idiopathic pulmonary fibrosis (IPF) is a fatal condition that leaves lung tissue permanently scarred and leads to the decline and eventual failure of the respiratory system. For those diagnosed with the disease, treatment ...

Diseases, Conditions, Syndromes

Researchers make important breakthrough in pulmonary fibrosis

A team of investigators led by members of the University of Colorado School of Medicine faculty at CU Anschutz Medical Campus has identified a connection between mucus in the small airways and pulmonary fibrosis.

Genetics

Researchers find common genetic link in lung ailments

An international research team led by members of the University of Colorado School of Medicine faculty has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary ...

Medical research

Study reveals new targets to inhibit pulmonary fibrosis

In a study out this week in Science Translational Medicine, an international team led by researchers at Vanderbilt University Medical Center sheds new light on the cause of pulmonary fibrosis and demonstrates a way to impede ...

Surgery

Anti-reflux surgery promising in idiopathic pulmonary fibrosis

(HealthDay)—Laparoscopic antireflux surgery is safe and well-tolerated in patients with idiopathic pulmonary fibrosis (IPF) and abnormal acid gastroesophageal reflux (GER), according to a phase 2 study published in the ...

Diseases, Conditions, Syndromes

Nintedanib plus sildenafil no better than nintedanib in IPF

(HealthDay)—Nintedanib plus sildenafil does not provide benefit over nintedanib alone for patients with idiopathic pulmonary fibrosis (IPF) and diffusion capacity of the lungs for carbon monoxide (DLCO) of 35 percent or ...

Diseases, Conditions, Syndromes

Mechanism of fibrosis development discovered

Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease of unknown origin with limited treatment options. Research suggests that the signaling molecule WNT5A plays a key role in the pathogenic process. Now, a group ...

Diseases, Conditions, Syndromes

Metformin reverses established lung fibrosis

Researchers at the University of Alabama at Birmingham have shown—for the first time—that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

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