Diseases, Conditions, Syndromes

Lung-on-a-chip simulates pulmonary fibrosis

Developing new medicines to treat pulmonary fibrosis, one of the most common and serious forms of lung disease, is not easy.

Medical research

Lung diseases share molecular signature

The fibrotic lung diseases BPD (bronchopulmonary dysplasia) and IPF (idiopathic pulmonary fibrosis) affect preterm infants and older adults, respectively. Evidence suggests that these diseases involve dysregulation of lung ...

Diseases, Conditions, Syndromes

Study tracks therapy to slow idiopathic pulmonary fibrosis

Investigators in the Division of Allergy, Pulmonary and Critical Care have launched a pilot study to see if patients with idiopathic pulmonary fibrosis (IPF) can tolerate the addition of a commonly used antiviral drug to ...

Diseases, Conditions, Syndromes

Pulmonary fibrosis caused by single transcription factor

To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now shown that reduced activity of the transcription ...

Diseases, Conditions, Syndromes

Thyroid hormone therapy heals lung fibrosis in animal study

Thyroid hormone therapy significantly resolves fibrosis, or scarring, in the lungs of mice, increasing their survival from disease, a Yale-led study shows. These provide a novel insight into the development of pulmonary fibrosis ...

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