Inflammatory disorders

New imaging agent spotlights inflammation

Many of the most common diseases—cancer, diabetes, cardiovascular and lung disease, and even COVID-19—have been linked to chronic or excessive inflammation. Blood tests can indicate that some part of a person's body is ...

Immunology

Toxic cell atlas guides new therapies for neurodegeneration

A common thread in many inflammatory and neurodegenerative diseases, including multiple sclerosis (MS), is damage caused by oxidative stress. Oxidative stress occurs when cells produce toxic substances known as reactive oxygen ...

Immunology

The role of monosodium urate crystals in gout

An attack of gout is said to be like your joint catching fire, and someone slamming it with a hammer to put out the flames. Now A*STAR researchers have identified how the build-up of monosodium urate (MSU) crystals in the ...

Immunology

Master detox molecule boosts immune defenses

Scientists at the Luxembourg Institute of Health (LIH) have discovered hitherto unknown molecular mechanism by which the human immune system activates its immune cells. T cells that express a gene known as Gclc effectively ...

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