Immunology

Experts uncover first molecular events of organ rejection

Researchers at the University of Pittsburgh School of Medicine and the University of Toronto have uncovered the first molecular steps that lead to immune system activation and eventual rejection of a transplanted organ. The ...

Immunology

Immune system discovery could end chronic organ rejection

Chronic rejection of transplanted organs is the leading cause of transplant failure, and one that the field of organ transplantation has not overcome in almost six decades since the advent of immunosuppressive drugs enabled ...

Medical research

Adult stem cells take root in livers and repair damage

Johns Hopkins researchers have demonstrated that human liver cells derived from adult cells coaxed into an embryonic state can engraft and begin regenerating liver tissue in mice with chronic liver damage.

Surgery

Pig hearts may save human lives: researchers

One day, cardiac patients may enjoy a new lease on life with pig hearts beating in their chests, said researchers reporting a major advance Tuesday in cross-species organ transplantation.

Medical research

Biotech startup uses nanoparticles to induce immune tolerance

More than 100 approved drugs in the U.S. warn of immune-related side effects on their labels. Countless others never make it onto shelves because of unwanted immune responses that can harm patients and limit the effectiveness ...

Medical research

Study provides hope for some human stem cell therapies

An international team of scientists headed by biologists at UC San Diego has discovered that an important class of stem cells known as human "induced pluripotent stem cells," or iPSCs, which are derived from an individual's ...

Medical research

Extracting stem cells from fat for tissue regeneration

Stem cells extracted from body fat may pave the way for the development of new regenerative therapies including soft tissue reconstruction following tumor removal or breast mastectomy surgery, the development of tissue-engineered ...

Medical research

Organ transplant rejection may not be permanent

Rejection of transplanted organs in hosts that were previously tolerant may not be permanent, report scientists from the University of Chicago. Using a mouse model of cardiac transplantation, they found that immune tolerance ...

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