Immunology

Faulty DNA disposal system found to cause inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy. ...

Genetics

Gene editing precisely repairs immune cells

Some hereditary genetic defects cause an exaggerated immune response that can be fatal. Using the CRISPR-Cas9 gene-editing tool, such defects can be corrected, thus normalizing the immune response, as researchers led by Klaus ...

Cardiology

Researchers identify new biomarker in quality of blood donations

A collaborative cohort of researchers, led by University of Colorado Anschutz Medical Campus professor Angelo D'Alessandro, has identified kynurenine as a critical new biomarker in the quality of stored red blood cells (RBCs), ...

Autism spectrum disorders

Clues to autism's causes may lie in the gut

Professor Alessio Fasano, a gastroenterologist at Massachusetts General Hospital in the US, has several relatives and friends raising children with autism—a neurological disorder characterized by impaired social behavior—so ...

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