Oncology & Cancer

Major step towards individual cancer immunotherapy

Medicine has great hopes for personalised cancer immunotherapy. The idea is to have a vaccine prompt the immune system to fight a tumour. Scientists at ETH Zurich have developed a method that allows them to determine which ...

Vaccination

Lessons we can learn from polio vaccination campaigns

A new study examining the impact of the global polio vaccine campaign has identified important lessons that "should be considered for COVID-19 vaccine roll-outs over coming years."

Diseases, Conditions, Syndromes

Team finds new safe method that enhances dengue vaccination

Researchers from the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have found a practical way to induce a strong and broad immunity to the dengue virus based on proof-of-concept ...

Diseases, Conditions, Syndromes

Coronavirus forcing parents to skip kids' vaccinations: UNICEF

The novel coronavirus pandemic that has forced billions of people across the globe to stay home is making parents skip routine immunisations for their kids, the United Nations children's agency UNICEF warned Thursday.

Diseases, Conditions, Syndromes

Child vaccination levels falling short in large parts of Africa

A study by the University of Southampton shows that several low-and middle-income countries, especially in Africa, need more effective child vaccination strategies to eliminate the threat from vaccine-preventable diseases.

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Immunization

Immunization, or immunisation, is the process by which an individual's immune system becomes fortified against an agent (known as the immunogen).

When this system is exposed to molecules that are foreign to the body (non-self), it will orchestrate an immune response, but it can also develop the ability to quickly respond to a subsequent encounter (through immunological memory). This is a function of the adaptive immune system. Therefore, by exposing an animal to an immunogen in a controlled way, its body can learn to protect itself: this is called active immunization.

The most important elements of the immune system that are improved by immunization are the B cells (and the antibodies they produce) and T cells. Memory B cell and memory T cells are responsible for a swift response to a second encounter with a foreign molecule. Passive immunization is when these elements are introduced directly into the body, instead of when the body itself has to make these elements.

Immunization be done through various techniques, most commonly vaccination. Vaccines against microorganisms that cause diseases can prepare the body's immune system, thus helping to fight or prevent an infection. The fact that mutations can cause cancer cells to produce proteins or other molecules that are unknown to the body forms the theoretical basis for therapeutic cancer vaccines. Other molecules can be used for immunization as well, for example in experimental vaccines against nicotine (NicVAX) or the hormone ghrelin (in experiments to create an obesity vaccine).

This text uses material from Wikipedia, licensed under CC BY-SA