Diseases, Conditions, Syndromes

Microbiologist explains the viruses that can wreak havoc globally

The novel coronavirus behind the COVID-19 pandemic is causing tremendous damage, killing tens of thousands of people, and upending economies as nations struggle to contain its spread. But on its own, like other viruses, it ...

HIV & AIDS

HIV-related heart disease risk varies by geography, income

People living with human immunodeficiency virus (HIV) infection are at higher risk of cardiovascular disease (CVD) compared to people without HIV. Data linking HIV and CVD, CVD risk factors and CVD risk assessment come predominantly ...

HIV & AIDS

Immunotherapy combo achieves reservoir shrinkage in HIV model

Stimulating immune cells with two cancer immunotherapies together can shrink the size of the viral "reservoir" in SIV-infected non-human primates treated with antiviral drugs, researchers have concluded. The reservoir includes ...

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Feline immunodeficiency virus

Feline immunodeficiency virus (FIV) is a lentivirus that affects domesticated housecats worldwide and is the causative agent of feline AIDS. Approximately 11% of cats worldwide, and about 2.5% of cats in the USA, are infected with FIV. FIV differs taxonomically from two other feline retroviruses, feline leukemia virus (FeLV) and feline foamy virus (FFV) and is more closely related to human immunodeficiency virus HIV. Within FIV, five subtypes have been identified based on amino acid sequence differences coding for the viral envelope. FIV is the only non-primate lentivirus to cause an AIDS-like syndrome, but FIV is not always a death sentence for cats, as they can live relatively healthily as carriers and transmitters of the disease for many years. A vaccine is available although its efficacy remains uncertain, and cats will test positive for FIV antibodies after vaccination.

FIV was first discovered in 1986 in a colony of cats that had a high prevalence of opportunistic infections and degenerative conditions, and has since been identified as an endemic disease in domestic cat populations worldwide .

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