Due to strain-specific behavioral idiosyncrasies, inbred mouse strains are suboptimal research models for behavioral aging studies.
Oct 11, 2019
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Mice represent well over half of the non-human subjects of biomedical research, and the vast majority of those mice are inbred. Formed by generation after generation of mating between brothers and sisters, inbred mice are ...
Dec 5, 2018
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Mouse models have advanced our understanding of immune function and disease in many ways but they have failed to account for the natural diversity in human immune responses. As a result, insights gained in the lab may be ...
Jul 26, 2017
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A strain of inbred mice commonly used for the creation of so-called knockout animals has been found to carry a previously undetected mutation that could affect the results of immune system research studies. In paper receiving ...
May 19, 2016
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(Medical Xpress)—One of the most challenging problems in biology is the extreme difficulty in predicting phenotype from genotype – and the questions it creates: If we could rear genetically identical individuals from ...
For the first time, scientists have combined genomic and proteomic analysis of blood plasma to enhance identification of genetically regulated protein traits. This could be applied to any large association study of civilization ...
Feb 8, 2013
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Scarring of the airways can lead to long-term breathing problems for some people exposed to high levels of chlorine gas from events such as an industrial accident, chemical spill following a train derailment or terroristic ...
Dec 19, 2012
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