Immunology

Identifying therapeutic targets in sepsis' cellular videogame

Sepsis is a medical condition that few patients have heard of and most doctors dread. The body's response to attack by bacteria can trigger a cascade of cellular self-destruction that inadvertently causes blood clots, multi-organ ...

Immunology

Cell death protein also damps inflammation

Inflammation is one strategy your body uses to fight infection, but if it gets out of control it can kill instead of heal. In the Sept. 18 issue of Immunity, UConn Health immunologist Vijay Rathinam and colleagues show how ...

Immunology

Immune system 'double agent' could be new ally in cancer fight

St. Jude Children's Research Hospital scientists have discovered that an enzyme called TAK1 functions like a "double agent" in the innate immune response, serving as an unexpected regulator of inflammation and cell death. ...

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