Inflammatory disorders

New discovery solves problem of anti-inflammatory substance

There have been great expectations regarding the production of a drug to block the enzyme LTA4 hydrolase, which plays a key role in the body's inflammatory response. However, in clinical trials, such molecules have proven ...

Immunology

How "good cholesterol" stops inflammation

High-density lipoprotein (HDL), known colloquially as "good cholesterol", protects against dangerous deposits in the arteries. An important function of HDL is its anti-inflammatory properties. An international research team ...

Immunology

Fighting allergies by silencing immune cells

University of Queensland researchers are one step closer to developing new medicines for treating inflammatory diseases, including allergies such as rhinitis, itchy hives, asthma, eczema and dermatitis.

Immunology

How cytoplasmic DNA triggers inflammation in human cells

A team led by LMU's Veit Hornung has elucidated the mechanism by which human cells induce inflammation upon detection of cytoplasmic DNA. Notably, the signal network involved differs from that used in the same context in ...

Oncology & Cancer

Atherosclerosis: Specific microRNAs promote inflammation

(Medical Xpress)—Atherosclerosis, an inflammatory reaction, is at the root of the most common forms of cardiovascular disease. Researchers at Ludwig-Maximilians-Universitaet in Munich have now identified a microRNA that ...

Arthritis & Rheumatism

Study shows efficacy of new rheumatoid arthritis drug

(Medical Xpress) -- A new study involving researchers from Karolinska Institutet demonstrates the efficacy of Tofacitinib, a new drug for rheumatoid arthritis. According to the study, which is published in The New England ...

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