Immunology

A switch for autoimmunity

When a virus or bacteria comes calling, protein "sensors" in your cells can detect the invader's DNA and activate inflammatory responses to prevent infection. One such sensor is cGAS (cyclic GMP-AMP synthase).

Oncology & Cancer

Block estrogen to treat lung disease

The strongest epidemiological risk factor for many forms of pulmonary arterial hypertension (PAH) is female gender. Increased estrogen makes females three times more likely to develop PAH, a chronic disease that eventually ...

Oncology & Cancer

Mechanisms ID'd for curcumin resensitization of cancer cells

(HealthDay)—Curcumin can resensitize chemoresistant pancreatic ductal adenocarcinoma (PDAC) cells through inhibition of the polycomb repressive complex 2 (PRC2)-PVT1-c-Myc axis, according to a study published online July ...

Neuroscience

Brain connectivity after 30 may predict psychological problems

Underdevelopment of the brain network underlying inhibition—the ability to concentrate on a particular stimulus and tune out competing stimuli—after 30 years of age is associated with self-reported psychological problems, ...

Oncology & Cancer

Study identifies new target for treatment of melanoma

A Brazilian study shows that inhibition of an RNA named RMEL3, which is encoded by a previously uncharacterized gene (also named RMEL3), can reduce the viability of cultured melanoma cells by up to 95%.

Diabetes

Vildagliptin, sitagliptin have similar effects on incretin

(HealthDay)—The dipeptidyl peptidase-4 (DPP-4) inhibitors vildagliptin and sitagliptin have similar effects on incretin hormone secretion, according to a study published online June 14 in Diabetes, Obesity and Metabolism.

Psychology & Psychiatry

Study details stress-diabetes link

A Rice University study has found a link between emotional stress and diabetes, with roots in the brain's ability to control anxiety.

page 5 from 13