Medical research

Scientists identify cell death pathway involved in lethal sepsis

Sepsis, a form of systemic inflammation, is the leading cause of death in critically ill patients. Sepsis is linked with massive cell death; however, the specific mechanisms involved in the lethality of sepsis are unclear. ...

Cardiology

Obesity negates beneficial drug effects

Blocking CETP—a protein that shuttles cholesterol and triglycerides between lipoproteins such as HDL and LDL—has been shown to improve levels of the "good" cholesterol HDL. Outcomes from clinical trials of CETP inhibitors, ...

Arthritis & Rheumatism

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an experimental study ...

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