Comprehensive profiling of fusion RNAs present in a large cohort of metastatic breast tumors revealed unique fusion mutations that may be therapeutically targetable, according to results presented at the San Antonio Breast ...
Dec 8, 2023
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A new risk model uses baseline sociodemographic and financial measures to predict which patients prescribed long-term therapy with aromatase inhibitors for breast cancer are at significantly higher risk of stopping that therapy ...
Dec 6, 2023
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Pancreatic cancer is one of the deadliest cancers—only about one in eight patients survives five years after diagnosis. Those dismal statistics are in part due to the thick, nearly impenetrable wall of fibrosis, or scar ...
Dec 6, 2023
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Research led by Queen Mary University of London's Wolfson Institute of Population Health has found that hormone levels, measured through blood tests, are an important indicator of whether women will benefit from recently ...
Dec 6, 2023
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For patients with hypertension and at least one other coronary heart disease risk factor, cardiovascular disease (CVD) mortality is similar for those receiving a thiazide-type diuretic, calcium channel blocker (CCB), or angiotensin-converting ...
Dec 4, 2023
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To identify potential therapeutic targets and preclinical drug candidates for the treatment of ovarian cancer, researchers led by Tan Li from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences ...
Nov 24, 2023
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As an extremely aggressive form of skin cancer, cutaneous melanoma, is still associated with a high mortality rate. Enormous progress has recently been made in the fight against deadly metastasis, but existing therapeutic ...
Nov 21, 2023
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A new study finds that a commonly prescribed class of antidepressant drugs taken during pregnancy may affect digestive health in offspring later in life. The study is published ahead of print in the American Journal of Physiology-Gastrointestinal ...
Nov 14, 2023
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New experimental evidence suggests that substances known as narrow-spectrum Wnt signaling inhibitors—which could have fewer side effects than other related substances—are capable of suppressing the growth of breast cancer ...
Nov 9, 2023
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A drug that can halve the risk of developing breast cancer in post-menopausal women has been approved for use in the UK. This drug, called anastrozole, could benefit an estimated 289,000 women in the UK who are at increased ...
Nov 9, 2023
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