Immunology

Faulty DNA disposal system found to cause inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy. ...

Genetics

New tool uncovers COVID-19 susceptibility mechanism

Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify ...

Medical research

A new immune pathway sheds light on amyotrophic lateral sclerosis

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures. But researchers at Boston Children's Hospital and Harvard Medical School are looking for new pathways for slowing ...

Oncology & Cancer

Experimental cancer vaccine shows promise in animal studies

An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice, report investigators from the National Institute of Allergy and Infectious ...

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