Immunology

Faulty DNA disposal system found to cause inflammation

Cells in the human body contain power-generating mitochondria, each with their own mtDNA—a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy. ...

Diseases, Conditions, Syndromes

Researchers trace a form of lupus back to a single mutation

Sometimes a single mutation in our genetic make-up is enough to cause disease. This is also the case with the autoimmune disease lupus. Lupus causes severe inflammation throughout the body and can have a serious impact on ...

Immunology

Mysterious fats reprogram the memory of innate immune cells

Researchers at Radboudumc have unveiled a fascinating connection between sphingolipids, mysterious fats named after the "Sphinx," and the memory of cells from the innate immune system. This discovery provides new avenues ...

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