Immunology

Mysterious fats reprogram the memory of innate immune cells

Researchers at Radboudumc have unveiled a fascinating connection between sphingolipids, mysterious fats named after the "Sphinx," and the memory of cells from the innate immune system. This discovery provides new avenues ...

Diseases, Conditions, Syndromes

Severe COVID-19 may lead to long-term innate immune system changes

Severe COVID-19 may cause long-lasting alterations to the innate immune system, the first line of defense against pathogens, according to a small study. These changes may help explain why the disease can damage so many different ...

Immunology

Researchers uncover a cellular process that leads to inflammation

Cedars-Sinai investigators have identified several steps in a cellular process responsible for triggering one of the body's important inflammatory responses. Their findings, published in the journal Science Immunology, open ...

Genetics

New tool uncovers COVID-19 susceptibility mechanism

Researchers have discovered a mechanism for COVID-19 susceptibility using a newly created tool. The tool, GASPACHO, captures dynamic changes in gene expression along the innate immune response, allowing researchers to identify ...

Immunology

Researchers map the immunology of the gut in children with IBD

Researchers from Karolinska Institutet and Sachs' Children and Youth Hospital have mapped the immune system in the gut of children with inflammatory bowel disease (IBD). The results, which were published in Cell Reports Medicine, ...

Medical research

A new immune pathway sheds light on amyotrophic lateral sclerosis

While drugs are on the market to slow the progression of neurodegenerative diseases, there are still no cures. But researchers at Boston Children's Hospital and Harvard Medical School are looking for new pathways for slowing ...

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