Immunology

Researchers map the immunology of the gut in children with IBD

Researchers from Karolinska Institutet and Sachs' Children and Youth Hospital have mapped the immune system in the gut of children with inflammatory bowel disease (IBD). The results, which were published in Cell Reports Medicine, ...

Immunology

Interleukin-11 found to ameliorate acute colitis in mice

Interleukin (IL)-11 is produced by inflammatory fibroblasts, one of the stromal cells, during acute colitis. Researchers at Toho University Japan found that IL-11 ameliorated acute colitis in mouse models. The IL-11 production ...

Immunology

Research team discovers central functions of innate immune cells

Inflammation and increased mucus production are typical symptoms of worm infections and allergies. This immune response involves our innate immune cells, but their exact functions are not yet fully understood. A research ...

Immunology

Cells help immune system tolerate friendly gut bacteria

Immune cells called group 3 innate lymphoid cells (ILC3s) play an essential role in establishing tolerance to symbiotic microbes that dwell in the human gastrointestinal tract, according to a study led by researchers at Weill ...

Immunology

Discovery of an innate immunological memory in the intestine

The innate immune system plays a crucial role in regulating host-microbe interactions, and especially in providing protection against pathogens that invade the mucosa. Using an intestinal infection model, scientists from ...

Medical research

Immune cell betrayal explains why it gets colder as we age

Human evolution has provided us a level of protection from the existential threat of cold temperature with the capacity to produce heat from fat stored in the body. However, with age, people become more susceptible to cold ...

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