Immunology

Molecular 'switch' reverses chronic inflammation and aging

Chronic inflammation, which results when old age, stress or environmental toxins keep the body's immune system in overdrive, can contribute to a variety of devastating diseases, from Alzheimer's and Parkinson's to diabetes ...

Medications

Towards a new drug class in the treatment of type 2 diabetes

Type 2 diabetes is a major public health problem that affects millions of people worldwide. Developing new drugs to help better treat its underlying causes is therefore a research priority. In a new study coordinated by Inserm ...

Diabetes

Tiny change has big effects, reverses prediabetes in mice

A small chemical change—shifting the position of two hydrogen atoms—makes the difference between mice that are healthy and mice with insulin resistance and fatty liver, major risk factors for diabetes and heart disease. ...

Diabetes

Diabetes may start in the intestines, research suggests

Scientists at Washington University School of Medicine in St. Louis have made a surprising discovery about the origin of diabetes. Their research suggests that problems controlling blood sugar — the hallmark of diabetes ...

Oncology & Cancer

Study finds association between high insulin dosage and cancer

Dr. Yuanjie Mao has led a study published in JAMA Oncology looking at the correlation between daily insulin dose and cancer incidence (the number of new cases) among patients with type 1 diabetes, finding that higher insulin ...

Diabetes

Study may point to new ways to reverse insulin resistance

Researchers at Vanderbilt University have discovered how insulin crosses the capillary endothelium to exit blood vessels and stimulate skeletal muscle cells—a major finding that may lead to new ways to reverse insulin resistance, ...

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