Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. ...
Jul 5, 2023
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A proof-of-concept study demonstrates that ductal cells derived from the human pancreas can be influenced by pharmacological stimulation to regenerate beta-like cells that functionally release insulin, providing new hope ...
Jun 16, 2023
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A study led by researchers at the Garvan Institute of Medical Research shows for the first time how a gene called RELA, known to regulate inflammation, also plays an essential role in maintaining normal blood-sugar levels.
Jun 14, 2023
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An improvement in glucose levels, reaching a normal range, and cessation in the need for medication can occur in some patients diagnosed with type 2 diabetes who are provided with lifestyle therapy, temporary pharmacotherapy, ...
Jun 14, 2023
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A study of the genetic variations that underlie differences in insulin secretion in mice has identified a number of candidate genes that may drive the development of conditions such as type 2 diabetes.
Jun 13, 2023
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Tirzepatide, a drug approved for diabetes and on the fast track for approval as a weight loss therapy, works through a unique ability to activate two different mechanisms the body uses to control insulin secretion and energy ...
Jun 5, 2023
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Canadian researchers have identified a new role for vitamin K and gamma-carboxylation in beta cells and their potentially protective role in diabetes, achieving a first in 15 years of basic research.
May 18, 2023
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If you're a health care provider treating people with type 2 diabetes (T2D), University at Buffalo researcher Mehmet A. Eskan has this suggestion for you: check your patients' teeth.
May 8, 2023
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Just over a century has passed since the discovery of insulin, a time period during which the therapeutic powers of the hormone have broadened and refined. Insulin is an essential treatment for type 1 diabetes and often for ...
Apr 22, 2023
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Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia associated with diabetes is not only inherently ...
Apr 20, 2023
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