Medical research

'Off-road' mode enables mobile cells to move freely

Leukocytes instantly move out of your blood vessels to the site of inflammation after an injury. Similarly, cancer cells, which can originate in any tissue or organ, can also spread and reproduce far away from their place ...

Genetics

Study homes in on possible cause of sudden cardiac deaths

By studying the sick hearts removed from four patients undergoing heart transplants, researchers have identified a protein and a signaling pathway that may contribute to sudden death in an inherited form of heart disease.

Medical research

Team tracks integrin's role in lung function

Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at Vanderbilt University Medical Center have discovered.

Oncology & Cancer

Missing molecule hobbles cell movement

Cells missing a certain protein on their surface can't move normally, UConn researchers report in Science Signaling. The research could give insight into how cells move and repair wounds in normal tissue, as well as how cancer ...

Immunology

Researchers discover how sleep can fight infection

Researchers in Germany have discovered why sleep can sometimes be the best medicine. Sleep improves the potential ability of some of the body's immune cells to attach to their targets, according to a new study that will be ...

Immunology

Fever alters immune cells so they can better reach infections

Fever is known to help power up our immune cells, and scientists in Shanghai have new evidence explaining how. They found in mice that fever alters surface proteins on immune cells like lymphocytes to make them better able ...

Medical research

Defense against joint degeneration

During cartilage development, chondrocytes secrete the extracellular matrix (ECM) and embed within the same environment. During progressive joint disease, such as osteoarthritis (OA), dysregulation of the process can lead ...

Oncology & Cancer

Mitochondria come together to kill cancer cells

Targeting a pathway that controls the movement of mitochondria, the powerhouses of all cells, could reduce cancer invasiveness and resistance to radiotherapy.

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