Diabetes

Designer type 2 diabetes drug comes with added benefits

A potential new treatment for type 2 diabetes has multiple, positive effects on health and metabolism in mice, reports a study in Nature. The new drug might have potential for treating a variety of disorders in addition to ...

Neuroscience

Researchers find new brain mechanisms regulating body weight

Researchers at the University of Gothenburg, Sweden, have clarified the link between the molecule interleukin-6 (IL-6) in the brain and obesity. In experiments on rats and mice, they show that the molecule does affect the ...

Medical research

How exercise reduces belly fat in humans

Some of you may have made a New Year's resolution to hit the gym to tackle that annoying belly fat. But have you ever wondered how physical activity produces this desired effect? A signaling molecule called interleukin-6 ...

Immunology

Scientists find molecular 'switch' for allergic asthma treatment

A team of Russian scientists has identified the role of the interleukin-6 molecule in the development of allergic asthma. It may comprise a new target for the treatment of this disease. The results are published in Frontiers ...

Medical research

Using light to stop itch

Itch is easily one of the most annoying sensations. For chronic skin diseases like eczema, it's a major symptom. Although it gives temporary relief, scratching only makes things worse because it can cause skin damage, additional ...

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Interleukin

Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes), The term interleukine, (inter-) as a means of communication, (-leukin) deriving from the fact that many of these proteins are produced by leukocytes and act on leukocytes. The name is something of a relic though (the term was coined by Dr. Paetkau, University of Victoria); it has since been found that interleukins are produced by a wide variety of body cells. The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4+ T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T, B, and hematopoietic cells.

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