Inflammatory disorders

Mini-guts reveal crucial forces that shape the intestinal lining

Using miniature guts grown in a dish and 3D biophysical modeling, FMI researchers and their collaborators have uncovered the forces that give the intestinal wall its classic brushlike appearance. The findings can help to ...

Diseases, Conditions, Syndromes

SARS-CoV-2 curtails immune response in the gut

In an effort to determine the potential for COVID-19 to begin in a person's gut, and to better understand how human cells respond to SARS-CoV-2, scientists at the European Molecular Biology Laboratory used human intestinal ...

Medical research

Defects in a specific cell type may cause ulcerative colitis

There are many variants of "goblet cells" in the intestines and they seem to have different functions, according to a new study from the University of Gothenburg. The study indicates that defects in goblet cells of a particular ...

Medical research

Gut epithelium muscles up against infection

To maximize absorption of nutrients from the diet, the intestinal mucous membrane has a large surface area. However, this also makes it vulnerable to attack from aggressive gut microbes. A new study by Uppsala University ...

Diseases, Conditions, Syndromes

Crohn's disease may be caused by immune signaling failure

People with Crohn's disease are typically treated with powerful anti-inflammatory medications that act throughout their body, not just in their digestive tract, creating the potential for unintended, and often serious, side ...

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