Medical research

Innate immunity: The final touch for antimicrobial defense

If bacteria enter the body, it often takes just a few minutes for the innate immune system to recognize them as foreign and set the immune defense in motion. Receptors of the immune system that recognize bacterial cell wall ...

Gastroenterology

Optimization of human small intestinal organoids

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids—miniature versions of the small intestine. This will help them to better study the functioning of the small ...

Immunology

Immune cells in the intestine have a sweet tooth

A new study led by Marc Veldhoen, group leader at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and Associate Professor at Faculdade de Medicina de Lisboa (FMUL) and published today in the scientific ...

Medical research

New stem cell mechanism discovered in the gut

A special layer of cells that coats the insides of the small and large intestines takes in nutrients and water while keeping anything bad from circulating. This layer is called the intestinal epithelium. It completely renews ...

Biomedical technology

Modeling a devastating childhood disease on a chip

Millions of children in low- and middle-income nations suffer from environmental enteric dysfunction (EED), a chronic inflammatory disease of the intestine that is the second leading cause of death in children under five ...

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