Gastroenterology

Your gut's microbiome, on a chip

The gut is one of the most complex organs in the body. Inside, it teems with a diverse microbial population that interacts and cooperates with intestinal cells to digest food and drugs. Disruptions in this microbiome have ...

Gastroenterology

Creating organoids with immune systems

In many ways, our intestines serve as the front gate between our bodies and the world around us. They help digest our food and absorb our medications. They send alarm signals when harmful bacteria, viruses, and allergens ...

Medical research

New study suggests a promising therapeutic target for sepsis

Sepsis, one of the most acute and serious disease complications in the intensive care unit, is caused by various infections and results in life-threatening organ dysfunction. The intestinal barrier plays a vital role in the ...

Immunology

Interleukin-11 found to ameliorate acute colitis in mice

Interleukin (IL)-11 is produced by inflammatory fibroblasts, one of the stromal cells, during acute colitis. Researchers at Toho University Japan found that IL-11 ameliorated acute colitis in mouse models. The IL-11 production ...

Immunology

Common immune cells found to sometimes prevent intestinal healing

B cells are critical to the proper functioning of the immune system. However, researchers at Karolinska Institutet have shown that they can sometimes do more harm than good, as their numbers greatly increase after bowel damage, ...

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