Gastroenterology

Novel microfluidic device models gut neuro-epithelial connections

Epithelial cells and sensory neurons communicate through neuro-epithelial connections in the GI tract, essential for major senses and digestion. Studying these interactions has been complicated due to the differing needs ...

Diseases, Conditions, Syndromes

Possible trigger of chronic inflammatory bowel disease identified

As the cause of chronic inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms. The discovery ...

Immunology

Unveiling a novel immune response in the intestinal epithelium

Researchers from the Jan Dobeš laboratory at Charles University in Prague have made a significant discovery uncovering a novel immune response in the intestinal epithelium. Furthermore, their study delineates a mechanism ...

Immunology

Immune cells identified as 'metabolic factories' in the gut

A research team from MedUni Vienna has now demonstrated for the first time the central role of macrophages in the renewal of intestinal cells, which sheds light on the complex interplay between immune cells and tissue regeneration. ...

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